Crocin II

• Description:

  Crocin II is isolated from the fruit of Gardenia jasminoides with antioxidant, anticancer, and antidepressant activity. Crocin II inhibits NO production with an IC50 value of 31.1 μM. Crocin II suppresses the expressions of protein and m-RNA of iNOS and COX-2[1].

• UNSPSC:

  12352005

• Target:

  COX; Endogenous Metabolite; NO Synthase

• Type:

  Natural Products

• Related Pathways:

  Immunology/Inflammation; Metabolic Enzyme/Protease

• Applications:

  COVID-19-immunoregulation

• Field of Research:

  Cancer; Inflammation/Immunology; Neurological Disease

• Assay Protocol:

  https://www.medchemexpress.com/crocin-ii.html

• Purity:

  99.04

• Solubility:

  DMSO : 25 mg/mL (ultrasonic)

• Smiles:

  O[C@@H] ([C@H] (O) [C@H]1O) [C@H] (O[C@H]1OC (/C (C) =C/C=C/C (C) =C/C=C/C=C (C) /C=C/C=C (C) /C (O[C@@H] ([C@@H] ([C@@H] (O) [C@@H]2O) O) O[C@@H]2CO) =O) =O) CO[C@@H] ([C@@H] ([C@@H] (O) [C@@H]3O) O) O[C@@H]3CO

• Molecular Formula:

  C38H54O19

• Molecular Weight:

  814.82

• References & Citations:

  [1]Hong YJ, et al. Anti-inflammatory activities of crocetin derivatives from processed Gardenia jasminoides. Arch Pharm Res. 2013 Aug;36 (8) :933-40.

• Shipping Conditions:

  Blue Ice

• Storage Conditions:

  -20°C (Powder, protect from light)

• Scientific Category:

  Natural Products

• Clinical Information:

  No Development Reported

• Isoform:

  INOS

• CAS Number:

  55750-84-0