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Moronic acid

CAT: 0804-HY-N3242-01Size: 1 mgDry Ice: NoHazardous: No
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CAT#:0804-HY-N3242-01Size:1 mg
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Description
Moronic Acid is a triterpenoid compound, which is an orally available anti-HIV agent with anti-inflammatory activity. Moronic Acid can inhibit viral replication, with an EC50 value of [1][2][3].
CAS Number
6713-27-5
Product Name Alternative
(+) -Moronic acid
UNSPSC
12352211
Hazard Statement
H302, H315, H319, H335
Target
HIV; NOD-like Receptor (NLR) ; Reactive Oxygen Species (ROS)
Type
Natural Products
Related Pathways
Anti-infection; Immunology/Inflammation; Metabolic Enzyme/Protease; NF-κB
Applications
COVID-19-anti-virus
Field of Research
Infection; Inflammation/Immunology
Assay Protocol
https://www.medchemexpress.com/moronic-acid.html
Purity
98.6
Smiles
C[C@]12[C@]3([C@@](CC[C@]1([H])[C@@]4([C@@](C(C)(C(CC4)=O)C)([H])CC2)C)([H])C5=CC(C)(C)CC[C@@]5(CC3)C(O)=O)C
Molecular Formula
C30H46O3
Molecular Weight
454.68
Precautions
H302, H315, H319, H335
References & Citations
[1]Ito J, et al. Anti-AIDS agents. 48. (1) Anti-HIV activity of moronic acid derivatives and the new melliferone-related triterpenoid isolated from Brazilian propolis. J Nat Prod. 2001 Oct;64 (10) :1278-81.|[2]Shuiliang Ruan, et al. Moronic acid improves intestinal inflammation in mice with chronic colitis by inhibiting intestinal macrophage polarization. J Biochem Mol Toxicol. 2022 Nov;36 (11) :e23188. |[3]M Kurokawa, et al. Anti-herpes simplex virus activity of moronic acid purified from Rhus javanica in vitro and in vivo. J Pharmacol Exp Ther. 1999 Apr;289 (1) :72-8.
Shipping Conditions
Blue Ice
Storage Conditions
-20°C, 3 years (Powder)
Scientific Category
Natural Products
Clinical Information
No Development Reported
Isoform
NLRP3

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