Bacterial Sortase Substrate III, Abz/DNP (TFA)

Bacterial Sortase Substrate III, Abz/DNP (TFA)

• UNSPSC Description: Bacterial Sortase Substrate III, Abz/DNP TFA is an internally quenched fluorescent peptide substrate. Staphylococcus aureus transpeptidase sortase A (SrtA) reacts with its native substrate Bacterial Sortase Substrate III, Abz/DNP, cleaving it and catalyzing the formation of an amide bond between the carboxyl group of threonine and the amino group of cell-wall crossbridges. Cleavage of this substrate can be monitored at Ex/Em=320 nm/420 nm.
• Target Antigen: Fluorescent Dye
• Type: Peptides
• Related Pathways: Others
• Applications: Neuroscience-Neuromodulation
• Field of Research: Infection
• Assay Protocol: https://www.medchemexpress.com/bacterial-sortase-substrate-iii-abz-dnp-tfa.html
• Purity: 96.63
• Solubility: DMSO : 50 mg/mL (ultrasonic)|H2O : < 0.1 mg/mL (ultrasonic)
• Smiles: O=C([C@@H](NC(C1=C(C=CC=C1)N)=O)CC(C)C)N2[C@H](C(N[C@H](C(N[C@H](C(NCC(N[C@H](C(N)=O)CCCCNC3=C(C=C(C=C3)[N+]([O-])=O)[N+]([O-])=O)=O)=O)[C@@H](C)O)=O)CCC(O)=O)=O)CCC2.OC(C(F)(F)F)=O.[x]
• References & Citations: [1]Zhang J, et al. Antiinfective therapy with a small molecule inhibitor of Staphylococcus aureus sortase. Proc Natl Acad Sci U S A. 2014 Sep 16;111(37):13517-22.
• Shipping Conditions: Blue Ice
• Storage Conditions: -80°C, 2 years; -20°C, 1 year (Powder, sealed storage, away from moisture)
• Clinical Information: No Development Reported