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Bifenthrin

CAT: 0804-HY-B0824-01Size: 5 mgDry Ice: NoHazardous: No
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CAT#:0804-HY-B0824-01Size:5 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
Bifenthrin is a synthetic pyrethroid insecticide. Bifenthrin prolongs the opening time of Nav1.8 sodium channels, leading to membrane depolarization and conductance block in the insect nervous system, thereby disrupting neural function. Bifenthrin was effective in inhibiting A. gambiae (LD50=0.15 ng/mg) and C. quinquefasciatus (LD50=0.16 ng/mg) . Bifenthrin has good lethality against susceptible and resistant mosquitoes and is very effective in inhibiting blood sucking and can be developed as a mosquito-removal netting material[1][2].
CAS Number
82657-04-3
UNSPSC
12352005
Hazard Statement
H300, H317, H331, H351, H372, H410
Target
Sodium Channel
Type
Reference compound
Related Pathways
Membrane Transporter/Ion Channel
Applications
Neuroscience-Neuromodulation
Field of Research
Neurological Disease
Assay Protocol
https://www.medchemexpress.com/bifenthrin.html
Purity
99.76
Solubility
DMSO : 100 mg/mL (ultrasonic)
Smiles
O=C([C@H]1C(C)(C)[C@H]1/C=C(Cl)/C(F)(F)F)OCC2=C(C)C(C3=CC=CC=C3)=CC=C2
Molecular Formula
C23H22ClF3O2
Molecular Weight
422.87
Precautions
H300, H317, H331, H351, H372, H410
References & Citations
[1]Hougard JM, et al. Bifenthrin: a useful pyrethroid insecticide for treatment of mosquito nets. J Med Entomol. 2002 May;39 (3) :526-33. |[2]Choi JS, et al. Structure-activity relationships for the action of 11 pyrethroid insecticides on rat Na v 1.8 sodium channels expressed in Xenopus oocytes. Toxicol Appl Pharmacol. 2006 Mar 15;211 (3) :233-44.
Shipping Conditions
Room Temperature
Storage Conditions
4°C (Powder, protect from light)
Scientific Category
Reference compound1
Clinical Information
No Development Reported

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