MIP-3 alpha/CCL20, Mouse (sf9, His)

MIP-3 alpha/CCL20, Mouse (sf9, His)

• UNSPSC Description: MIP-3 alpha/CCL20 Protein, Mouse (sf9, His) is a CC chemokine that attracts lymphocytes and mild neutrophils by binding to and acting on the chemokine receptor CCR6. It induces intracellular calcium mobilization and mediates cancer, various autoimmune diseases, and antimicrobial effects. MIP-3 alpha/CCL20 Protein, Mouse (sf9, His) is a recombinant mouse CCL20 expressed by Sf9 insect cells with a his tag at the C-terminus[1].
• Type: Recombinant Proteins
• Assay Protocol: https://www.medchemexpress.com/cytokines/mip-3-alpha-ccl20-protein-mouse-sf9-his.html
• Molecular Weight: Approximately 14 kDa
• References & Citations: [1]Louis Boafo Kwantwi, et al. Multifaceted roles of CCL20 (C-C motif chemokine ligand 20): mechanisms and communication networks in breast cancer progression. Bioengineered. 2021 Dec;12(1):6923-6934.|[2]M Baba, et al. Identification of CCR6, the specific receptor for a novel lymphocyte-directed CC chemokine LARC. J Biol Chem. 1997 Jun 6;272(23):14893-8.|[3]Gisela Soboll, et al. Effect of oestradiol on PAMP-mediated CCL20/MIP-3 alpha production by mouse uterine epithelial cells in culture. Immunology. 2006 Jun;118(2):185-94.|[4]Jinlin Liu, et al. Tumor-associated macrophages recruit CCR6+ regulatory T cells and promote the development of colorectal cancer via enhancing CCL20 production in mice. PLoS One. 2011 Apr 29;6(4):e19495.
• Shipping Conditions: Room temperature