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Sulfamethoxazole-d4

CAT: 0804-HY-B0322S-01Size: 1 mgDry Ice: NoHazardous: No
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CAT#:0804-HY-B0322S-01Size:1 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
Sulfamethoxazole-d4 (Ro 4-2130-d4) is a deuterium labeled Sulfamethoxazole. Sulfamethoxazole (Ro 4-2130) is a sulfonamide antibiotic with a widespread antibacterial activity. Sulfamethoxazole inhibits bacterial folate metabolism by competing with 4-Aminobenzoic acid (HY-B1008) (PABA) to act on dihydropteroate synthetase and dihydropteroate reductase. Sulfamethoxazole can be used for the study of urinary tract infections (UTIs), prostatitis, and bronchitis[1][2][3].
CAS Number
1020719-86-1
Product Name Alternative
Ro 4-2130-d4
UNSPSC
12352005
Hazard Statement
H315, H317, H319, H335
Target
Antibiotic; Bacterial; Isotope-Labeled Compounds
Type
Isotope-Labeled Compounds
Related Pathways
Anti-infection; Others
Applications
COVID-19-immunoregulation
Field of Research
Infection
Purity
99.32
Solubility
DMSO : 50mg/mL (ultrasonic)
Smiles
O=S(C1=C([2H])C([2H])=C(N)C([2H])=C1[2H])(NC2=NOC(C)=C2)=O
Molecular Formula
C10H7D4N3O3S
Molecular Weight
257.30
Precautions
H315, H317, H319, H335
References & Citations
[1]Zambuzzi-Carvalho et al. Transcriptional profile of the human pathogenic fungus Paracoccidioides lutzii in response to sulfamethoxazole. Med Mycol. 2015;53 (5) :477-492. |[2]Choonara BF, et al. A menthol-based solid dispersion technique for enhanced solubility and dissolution of sulfamethoxazole from an oral tablet matrix. AAPS PharmSciTech. 2015 Aug;16 (4) :771-86.|[3]Ogata H, et al. Dose Dependent Effect of Sulfamethoxazole on Inhibiting KATP Channel of Mouse Pancreatic β Cell. Dose Response. 2023 Sep 28;21 (3) :15593258231203611.
Shipping Conditions
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Scientific Category
Isotope-Labeled Compounds
Clinical Information
No Development Reported

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Alternative Products

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CS-K-00143Sulfamethoxazole-d4
AR-S10962-01Sulfamethoxazole EP Impurity A-d4 (Sulfamethoxazole USP Related Compound A-d4)
sc-474589Sulfamethoxazole-d4 N4-glucoside
021178Sulfamethoxazole-d4 β-D-Glucuronide
sc-219014N-Acetyl Sulfamethoxazole-d4
AR-S10964-01Sulfamethoxazole Impurity 3-d4
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