Sulfamethoxazole

CAT: 0804-HY-B0322-01Size: 100 mgDry Ice: NoHazardous: No

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CAT#:0804-HY-B0322-01Size:100 mg

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Description

Sulfamethoxazole (Ro 4-2130) is a sulfonamide antibiotic with a widespread antibacterial activity. Sulfamethoxazole inhibits bacterial folate metabolism by competing with 4-Aminobenzoic acid (PABA) to act on dihydropteroate synthetase and dihydropteroate reductase. Sulfamethoxazole can be used for the study of urinary tract infections (UTIs), prostatitis, and bronchitis[1][2][3].

CAS Number

723-46-6

Product Name Alternative

Ro 4-2130

UNSPSC

12352005

Hazard Statement

H303, H317, H361

Target

Antibiotic; Bacterial

Type

Reference compound

Related Pathways

Anti-infection

Applications

COVID-19-immunoregulation

Field of Research

Infection; Cancer

Assay Protocol

https://www.medchemexpress.com/Sulfamethoxazole.html

Purity

99.91

Solubility

DMSO : ≥ 100 mg/mL|H2O : < 0.1 mg/mL

Smiles

O=S(C1=CC=C(N)C=C1)(NC2=NOC(C)=C2)=O

Molecular Formula

C10H11N3O3S

Molecular Weight

253.28

Precautions

H303, H317, H361

References & Citations

[1]Zambuzzi-Carvalho et al. Transcriptional profile of the human pathogenic fungus Paracoccidioides lutzii in response to sulfamethoxazole. Med Mycol. 2015;53 (5) :477-492. |[2]Choonara BF, et al. A menthol-based solid dispersion technique for enhanced solubility and dissolution of sulfamethoxazole from an oral tablet matrix. AAPS PharmSciTech. 2015 Aug;16 (4) :771-86.|[3]Ogata H, et al. Dose Dependent Effect of Sulfamethoxazole on Inhibiting KATP Channel of Mouse Pancreatic β Cell. Dose Response. 2023 Sep 28;21 (3) :15593258231203611.

Shipping Conditions

Room Temperature

Storage Conditions

-20°C, 3 years; 4°C, 2 years (Powder)

Scientific Category

Reference compound1

Clinical Information

Launched

Citation 01

Alternative Products

Catalog	Name
B2040-50	Sulfamethoxazole
T200416-01	Sulfamethoxazole-NO

Sulfamethoxazole

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