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BNC105P

CAT: 0804-HY-15406Size: 1 EachDry Ice: NoHazardous: No
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CAT#:0804-HY-15406Size:1 Each
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Description
BNC105P is a phosphate prodrug of BNC105 , that exhibits activity as a vascular disrupting agent (VDA) and an antitumor agent through conversion to active BNC105[1].
CAS Number
945771-96-0
UNSPSC
12352005
Target
Microtubule/Tubulin
Type
Reference compound
Related Pathways
Cell Cycle/DNA Damage; Cytoskeleton
Applications
Cancer-programmed cell death
Field of Research
Cancer; Cardiovascular Disease
Assay Protocol
https://www.medchemexpress.com/bnc105p.html
Smiles
COC1=CC(C(C2=C(C)OC3=C(OP(O[Na])(O[Na])=O)C(OC)=CC=C23)=O)=CC(OC)=C1OC
Molecular Formula
C20H19Na2O10P
Molecular Weight
496.31
References & Citations
[1]Rischin D, et al., Clinical, pharmacodynamic, and pharmacokinetic evaluation of BNC105P: a phase I trial of a novel vascular disrupting agent and inhibitor of cancer cell proliferation. Clin Cancer Res. 2011 Aug 1;17 (15) :5152-60.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
Phase 2

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