Products for Research Use Only
RegisterLogin

Ceratamine A

CAT: 0804-HY-N6997-01Size: 10 mgDry Ice: NoHazardous: No
Product image 1
1 / 1
CAT#:0804-HY-N6997-01Size:10 mg
Selected
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
Quick Request Actions
Description
Ceratamine A is an antimitotic heterocyclic alkaloid isolated from the marine sponge Pseudoceratina sp., acts as a microtubule-stabilizing agent. Ceratamine A exhibits cytotoxicity against human cancer cell lines[1][2][3].
CAS Number
634151-15-8
UNSPSC
12352005
Target
Microtubule/Tubulin
Type
Natural Products
Related Pathways
Cell Cycle/DNA Damage; Cytoskeleton
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/ceratamine-a.html
Solubility
10 mM in DMSO
Smiles
O=C(N(C)C=C1)C(CC2=CC(Br)=C(OC)C(Br)=C2)=C3C1=NC(NC)=N3
Molecular Formula
C17H16Br2N4O2
Molecular Weight
468.14
References & Citations
[1]Manzo E, et al. Ceratamines A and B, antimitotic heterocyclic alkaloids isolated from the marine sponge Pseudoceratina sp. collected in Papua New Guinea. Org Lett. 2003 Nov 27;5 (24) :4591-4.|[2]Nodwell M, et al. Synthetic approaches to the microtubule-stabilizing sponge alkaloid ceratamine A and desbromo analogues. J Org Chem. 2009 Feb 6;74 (3) :995-1006.|[3]Pan X, et al. Synthesis and cytotoxicity of novel imidazo[4,5-d]azepine compounds derived from marine natural product ceratamine A. Bioorg Med Chem Lett. 2018 Mar 1;28 (5) :866-868.
Shipping Conditions
Room temperature
Scientific Category
Natural Products
Clinical Information
No Development Reported

Related Products

CatalogName
HY-W747533-01C8 Ceramine, D-erythro

Alternative Products

CatalogName
T10763Ceratamine A
T201196-01Ceratamine B

Popular Products