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Thiamphenicol-d3

CAT: 0804-HY-B0479S-01Size: 1 mgDry Ice: NoHazardous: No
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CAT#:0804-HY-B0479S-01Size:1 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
Thiamphenicol-d3 is a deuterium labeled Thiamphenicol. Thiamphenicol, a methyl-sulfonyl derivative of Chloramphenicol, is a broad-spectrum antimicrobial antibiotic. Thiamphenicol acts by binding to the 50S ribosomal subunit, leading to inhibition of protein synthesis and bacteriostatic effect (against Gram-negative, Gram-positive aerobic and anaerobic bacteria) [1][2].
CAS Number
2211914-19-9
Product Name Alternative
Thiophenicol-d3; Dextrosulphenidol-d3
UNSPSC
12352005
Target
Antibiotic; Bacterial; Isotope-Labeled Compounds
Type
Isotope-Labeled Compounds
Related Pathways
Anti-infection; Others
Applications
COVID-19-immunoregulation
Field of Research
Infection
Purity
99.51
Solubility
10 mM in DMSO
Smiles
ClC(Cl)C(N[C@H](CO)[C@@H](C1=CC=C(C=C1)S(=O)(C([2H])([2H])[2H])=O)O)=O
Molecular Formula
C12H12D3Cl2NO5S
Molecular Weight
359.24
References & Citations
[1]A Marchese, et al. In vitro activity of thiamphenicol against multiresistant Streptococcus pneumoniae, Haemophilus influenzae and Staphylococcus aureus in Italy. J Chemother. 2002 Dec;14 (6) :554-61.|[2]Marta Tikhomirov, et al. Pharmacokinetics of florfenicol and thiamphenicol in ducks. J Vet Pharmacol Ther. 2019 Jan;42 (1) :116-120.
Shipping Conditions
Blue Ice
Storage Conditions
-20°C (Powder, sealed storage, away from moisture)
Scientific Category
Isotope-Labeled Compounds
Clinical Information
No Development Reported

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