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Thiamphenicol

CAT: 0804-HY-B0479-01Size: 100 mgDry Ice: NoHazardous: No
CAT#:0804-HY-B0479-01Size:100 mg
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Description
Thiamphenicol (Thiophenicol), a methyl-sulfonyl derivative of Chloramphenicol, is a broad-spectrum antimicrobial antibiotic. Thiamphenicol acts by binding to the 50S ribosomal subunit, leading to inhibition of protein synthesis and bacteriostatic effect (against Gram-negative, Gram-positive aerobic and anaerobic bacteria) [1][2].
CAS Number
[15318-45-3]
Product Name Alternative
Thiophenicol; Dextrosulphenidol
UNSPSC
12352005
Hazard Statement
H302, H315, H319, H335
Target
Antibiotic; Bacterial; Beta-lactamase
Type
Reference compound
Related Pathways
Anti-infection
Applications
COVID-19-immunoregulation
Field of Research
Infection
Assay Protocol
https://www.medchemexpress.com/Thiamphenicol.html
Purity
99.63
Solubility
DMSO : 100 mg/mL (ultrasonic) |H2O : 2 mg/mL (ultrasonic)
Smiles
O=C(N[C@H](CO)[C@H](O)C1=CC=C(S(=O)(C)=O)C=C1)C(Cl)Cl
Molecular Formula
C12H15Cl2NO5S
Molecular Weight
356.22
Precautions
H302, H315, H319, H335
References & Citations
[1]A Marchese, et al. In vitro activity of thiamphenicol against multiresistant Streptococcus pneumoniae, Haemophilus influenzae and Staphylococcus aureus in Italy. J Chemother. 2002 Dec;14 (6) :554-61.|[2]Marta Tikhomirov, et al. Pharmacokinetics of florfenicol and thiamphenicol in ducks. J Vet Pharmacol Ther. 2019 Jan;42 (1) :116-120.
Shipping Conditions
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Scientific Category
Reference compound1
Clinical Information
Launched

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TRC-T344160-50MGThiamphenicol

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