LPH-5

• Description :

  LPH-5 is a selective 5-HT2A receptor agonist (EC50=190 nM) . LPH-5 works by selectively activating the 5-HT2A receptor, which may be involved in regulating mood, perception, and other central nervous system functions associated with the 5-HT2A receptor. LPH-5 can be used to further explore the 5-HT2A receptor in psychiatric disorders, including depression, anxiety, and substance abuse disorders[1].

• CAS Number :

  [2641630-97-7]

• UNSPSC :

  12352005

• Target :

  5-HT Receptor

• Type :

  Reference compound

• Related Pathways :

  GPCR/G Protein; Neuronal Signaling

• Applications :

  Neuroscience-Neuromodulation

• Field of Research :

  Neurological Disease

• Assay Protocol :

  https://www.medchemexpress.com/lph-5.html

• Smiles :

  COC1=C(C=C(C(C(F)(F)F)=C1)OC)[C@]2(CNCCC2)[H]

• Molecular Formula :

  C14H18F3NO2

• Molecular Weight :

  289.29

• References & Citations :

  [1]M. Ro̷rsted E, et al. Discovery and Structure–Activity Relationships of 2, 5-Dimethoxyphenylpiperidines as Selective Serotonin 5-HT2A Receptor Agonists[J]. Journal of Medicinal Chemistry, 2024.

• Shipping Conditions :

  Room temperature

• Scientific Category :

  Reference compound1

• Clinical Information :

  Phase 1

• Isoform :

  5-HT2 Receptor