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L-364918

CAT: 0804-HY-129333Size: 1 EachDry Ice: NoHazardous: No
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CAT#:0804-HY-129333Size:1 Each
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
L-364918 is a potent and selective oxytocin and arginine vasopressin antagonist with Ki values of 30, 1300, 2400 nM for OT, AVP-V1, AVP-V2, respectively. L-364918 has the potential for the research of preterm labor and disturbances in water balance[1].
CAS Number
122211-31-8
UNSPSC
12352005
Target
Oxytocin Receptor; Vasopressin Receptor
Type
Reference compound
Related Pathways
GPCR/G Protein
Field of Research
Metabolic Disease
Assay Protocol
https://www.medchemexpress.com/l-364918.html
Smiles
O=C1NC(C(CC)C)C(N2NCCCC2C(N3NCCCC3C(N(C(CC4=CC=CC=C4)C(N5CCCC5C(NC1CC6=CC=CC=C6)=O)=O)C)=O)=O)=O
Molecular Formula
C40H54N8O6
Molecular Weight
742.91
References & Citations
[1]Pettibone DJ, et al. A structurally unique, potent, and selective oxytocin antagonist derived from Streptomyces silvensis. Endocrinology. 1989 Jul;125 (1) :217-22.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Isoform
V2 Receptor

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