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Dibenz[a, h]anthracene (Standard)

CAT: 0804-HY-W013053R-01Size: 5 mgDry Ice: NoHazardous: No
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CAT#:0804-HY-W013053R-01Size:5 mg
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Description
Dibenz[a, h]anthracene (Standard) is the analytical standard of Dibenz[a, h]anthracene. This product is intended for research and analytical applications. Dibenz[a, h]anthracene (DBA) is a polycyclic aromatic hydrocarbon (PAH) of considerable tumorigenicity. Dibenz[a, h]anthracene results in DNA adduct formation leading to the activation of a DNA damage response. Dibenz[a, h]anthracene induces cell cycle arrest and apoptosis via both Tp53-dependent and Tp53-independent mechanisms[1][2].
CAS Number
53-70-3
Product Name Alternative
DBA (Standard) ; 1,2,5,6-Dibenzanthracene (Standard) ; Benzo[k]tetraphene (Standard)
UNSPSC
12352005
Target
Apoptosis; DNA/RNA Synthesis; MDM-2/p53; Reference Standards
Type
Reference Standards
Related Pathways
Apoptosis; Cell Cycle/DNA Damage; Others
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/dibenz-a-h-anthracene-standard.html
Smiles
C12=CC=CC=C1C3=CC(C=CC4=CC=CC=C45)=C5C=C3C=C2
Molecular Formula
C22H14
Molecular Weight
278.35
References & Citations
[1]K L Platt, et al. Stereoselective metabolism of dibenz (a, h) anthracene to trans-dihydrodiols and their activation to bacterial mutagens. Environ Health Perspect. 1990 Aug:88:37-41.|[2]Amal I Malik, et al. Hepatic genotoxicity and toxicogenomic responses in Muta™Mouse males treated with dibenz[a, h]anthracene. Mutagenesis. 2013 Sep;28 (5) :543-54.
Shipping Conditions
Room temperature
Scientific Category
Reference Standards

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