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Rac-Pemafibrate

CAT: 0804-HY-17618ASize: 1 EachDry Ice: NoHazardous: No
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CAT#:0804-HY-17618ASize:1 Each
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Description
Pemafibrate racemate (K13675 racemate) is the racemate of pemafibrate, and activates PPARα activity, with EC50s of 1 nM, >10 μM and 1.7 μM for h-PPARα, h-PPARγ and h-PPARδ, respectively.
CAS Number
848258-31-1
Product Name Alternative
Rac-K13675
UNSPSC
12352005
Target
PPAR
Type
Reference compound
Related Pathways
Cell Cycle/DNA Damage; Metabolic Enzyme/Protease; Vitamin D Related/Nuclear Receptor
Applications
COVID-19-anti-virus
Field of Research
Inflammation/Immunology
Assay Protocol
https://www.medchemexpress.com/Pemafibrate-racemate.html
Solubility
10 mM in DMSO
Smiles
CCC(OC1=CC=CC(CN(C2=NC3=CC=CC=C3O2)CCCOC4=CC=C(OC)C=C4)=C1)C(O)=O
Molecular Formula
C28H30N2O6
Molecular Weight
490.55
References & Citations
[1]Yamazaki Y, et al. Design and synthesis of highly potent and selective human peroxisome proliferator-activated receptor alpha agonists. Bioorg Med Chem Lett. 2007 Aug 15;17 (16) :4689-93. Epub2007 May 24.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
Phase 3
Isoform
PPARα; PPARβ/δ

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