5-HT2C agonist-3

5-HT2C agonist-3

• CAS Number: 2104810-18-4
• UNSPSC Description: 5-HT2C agonist-3 ((+)-19) is a selective 5-HT2C agonist (EC50: 24 nM, Ki: 78 nM). 5-HT2C agonist-3 has antipsychotic drug-like activity. 5-HT2C agonist-3 blocks Amphetamine-induced hyperactivity[1].
• Target Antigen: 5-HT Receptor
• Type: Reference compound
• Related Pathways: GPCR/G Protein;Neuronal Signaling
• Applications: Neuroscience-Neuromodulation
• Field of Research: Neurological Disease
• Assay Protocol: https://www.medchemexpress.com/5-ht2c-agonist-3.html
• Solubility: DMSO : 100 mg/mL (ultrasonic)
• Smiles: COC(C=CC=C1)=C1CNC[C@@H]2[C@@H](C3=C(C=CC(F)=C3)OC)C2.[H]Cl
• Molecular Weight: 351.84
• References & Citations: [1]Guiping Zhang, et al. Discovery of N-Substituted (2-Phenylcyclopropyl)methylamines as Functionally Selective Serotonin 2C Receptor Agonists for Potential Use as Antipsychotic Medications. J. Med. Chem. 2017, 60, 14, 6273–6288.
• Shipping Conditions: Room Temperature
• Clinical Information: No Development Reported