Acridine Orange (hydrochloride)
CAT:
804-HY-101879-01
Size:
100 mg
Price:
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- Availability: 24/48H Stock Items & 2 to 6 Weeks non Stock Items.
- Dry Ice Shipment: No
Acridine Orange (hydrochloride)
- CAS Number: 65-61-2
- UNSPSC Description: Acridine Orange hydrochloride is a cell-penetrable nucleic acid-selective fluorescent dye. Acridine Orange hydrochloride produces orange fluorescence when it binds to ssDNA or RNA, and green fluorescence when it binds to dsDNA (Ex: 488 nM; Em: green fluorescence at 530 nm, orange fluorescence at 640 nm)[1][2][3].
- Target Antigen: DNA Stain; Fluorescent Dye; Parasite
- Type: Dye Reagents
- Related Pathways: Anti-infection;Cell Cycle/DNA Damage;Others
- Field of Research: Others
- Assay Protocol: https://www.medchemexpress.com/Acridine_Orange_hydrochloride.html
- Purity: 99.86
- Solubility: DMSO : 25 mg/mL (ultrasonic)|H2O : 50 mg/mL (ultrasonic;heat to 60°C)
- Smiles: CN(C)C1=CC=C2C(N=C3C=C(N(C)C)C=CC3=C2)=C1.[H]Cl
- Molecular Weight: 301.821
- References & Citations: [1]McMaster GK, et al. Analysis of single- and double-stranded nucleic acids on polyacrylamide and agarosegels by using glyoxal and acridine orange. Proc Natl Acad Sci U S A. 1977 Nov;74(11):4835-8.|[2]Traganos F, et al. Simultaneous staining of ribonucleic and deoxyribonucleic acids in unfixed cells using acridine orange in a flow cytofluorometric system. J Histochem Cytochem. 1977 Jan;25(1):46-56.|[3]Byvaltsev VA, et al. Acridine Orange: A Review of Novel Applications for Surgical Cancer Imaging and Therapy. Front Oncol. 2019 Sep 24;9:925. |[4]Wang Q, et al. Substrate stiffness regulates the differentiation profile and functions of osteoclasts via cytoskeletal arrangement. Cell Prolif. 2022 Jan;55(1):e13172. Acta Pharm Sin B. 2021 Feb 11.|Adv Funct Mater. 2023 Apr 14.|Adv Sci (Weinh). 2024 Aug 9:e2404693.|Cell Death Dis. 2020 Jul 30;11(7):607.|Cell Death Dis. 2021 Jan 13;12(1):80.|Cell Prolif. 2021 Dec 24;e13172.|Clin Transl Med. 2023 Mar;13(3):e1229.|Environ Toxicol. 2023 May 20.|Eur J Med Chem. 2024 Dec 5:279:116866.|Eur J Med Chem. 2024 May 17:273:116507|Free Radic Biol Med. 2023 Sep 1;208:402-417.|Int J Mol Med. 2023 Apr 7.|Int J Mol Sci. 2023 Sep 5, 24(18), 13812.|J Control Release. 2024 Oct 11:376:167-183.|Microbiol Spectr. 2023 May 1;e0313822.|Nat Commun. 2023 Jun 30;14(1):3877.|SSRN. 2023 Mar 9.|SSRN. 2023 Nov 15.|STAR Protoc. 2024 Sep 12;5(3):103309.|Chemosphere. 2023 Apr;320:138071.|Research Square Print. December 12th, 2022.
- Shipping Conditions: Room Temperature
- Storage Conditions: 4°C (Powder, protect from light, stored under nitrogen)
- Clinical Information: No Development Reported