Acridine Orange base
CAT:
804-HY-D0952
Size:
100 mg
Price:
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- Availability: 24/48H Stock Items & 2 to 6 Weeks non Stock Items.
- Dry Ice Shipment: No
Acridine Orange base
- CAS Number: 494-38-2
- UNSPSC Description: Acridine Orange base is a cell-permeable fluorescent dye that stains organisms (bacteria, parasites, viruses, etc.) bright orange and, when used under appropriate conditions (pH=3.5, Ex=460 nm), distinguishes human cells in green for detection by fluorescence microscopy. Acridine Orange base fluoresces green when bound to dsDNA (Ex=488, Em=520-524) and red when bound to ssDNA (Ex=457, Em=630-644) or ssRNA (Ex=457, Em=630-644), also can be used in cell cycle assays[1][2][3].
- Target Antigen: Parasite
- Type: Dye Reagents
- Related Pathways: Anti-infection
- Field of Research: Others
- Assay Protocol: https://www.medchemexpress.com/acridine-orange-base.html
- Purity: 96.58
- Solubility: 1 M HCL : 200 mg/mL (ultrasonic)|DMSO : 35 mg/mL (ultrasonic)|H2O : 5.83 mg/mL (ultrasonic;warming;heat to 60°C)
- Smiles: CN(C)C1=CC=C2C(N=C3C=C(N(C)C)C=CC3=C2)=C1
- Molecular Weight: 265.36
- References & Citations: [1]Darzynkiewicz Z, et al. Differential staining of DNA and RNA. Curr Protoc Cytom. 2004 Nov;Chapter 7:Unit 7.3.|[2]Mirrett S. Acridine orange stain. Infect Control. 1982 May-Jun;3(3):250-2. |[3]Yektaeian N, et al. Lipophilic tracer Dil and fluorescence labeling of acridine orange used for Leishmania major tracing in the fibroblast cells. Heliyon. 2019 Dec 18;5(12):e03073. Chemosphere. 2023 Apr;320:138071.|Research Square Print. December 12th, 2022.|Acta Pharm Sin B. 2021 Feb 11.|Adv Funct Mater. 2023 Apr 14.|Adv Sci (Weinh). 2024 Aug 9:e2404693.|Cell Death Dis. 2020 Jul 30;11(7):607.|Cell Death Dis. 2021 Jan 13;12(1):80.|Cell Prolif. 2021 Dec 24;e13172.|Clin Transl Med. 2023 Mar;13(3):e1229.|Environ Toxicol. 2023 May 20.|Eur J Med Chem. 2024 Dec 5:279:116866.|Eur J Med Chem. 2024 May 17:273:116507|Free Radic Biol Med. 2023 Sep 1;208:402-417.|Int J Mol Med. 2023 Apr 7.|Int J Mol Sci. 2023 Sep 5, 24(18), 13812.|J Control Release. 2024 Oct 11:376:167-183.|Microbiol Spectr. 2023 May 1;e0313822.|Nat Commun. 2023 Jun 30;14(1):3877.|SSRN. 2023 Mar 9.|SSRN. 2023 Nov 15.|STAR Protoc. 2024 Sep 12;5(3):103309.
- Shipping Conditions: Room Temperature
- Storage Conditions: 4°C (Powder, protect from light)
- Clinical Information: No Development Reported