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Acetohydroxamic acid

CAT: 0804-HY-B1235-01Size: 100 mgDry Ice: NoHazardous: No
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CAT#:0804-HY-B1235-01Size:100 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
Acetohydroxamic acid is the inhibitor for bacterial and plant urease that can be used for chronic urinary tract infections. Acetohydroxamic acid selectively inhibits arachidonic acid 5-lipoxygenase that is useful in the research of asthma. Acetohydroxamic acid inhibits the formation of advanced glycation end products, and reduces oxidative stress and inflammatory responses. Acetohydroxamic acid exhibits antiviral activity against HIV[1][2][3].
CAS Number
546-88-3
Product Name Alternative
N-Hydroxyacetamide
UNSPSC
12352211
Hazard Statement
H360
Target
Bacterial; HIV
Type
Reference compound
Related Pathways
Anti-infection
Applications
COVID-19-immunoregulation
Field of Research
Infection; Inflammation/Immunology
Assay Protocol
https://www.medchemexpress.com/Acetohydroxamic-acid.html
Concentration
10mM
Purity
98.66
Solubility
DMSO : 233.33 mg/mL (ultrasonic) |H2O : 100 mg/mL (ultrasonic)
Smiles
CC(NO)=O
Molecular Formula
C2H5NO2
Molecular Weight
75.07
Precautions
H360
References & Citations
[1]Sharma M, et al. Biotransformation of Acetamide to Acetohydroxamic Acid at Bench Scale Using Acyl Transferase Activity of Amidase of Geobacillus pallidus BTP-5x MTCC 9225. Indian J Microbiol. 2012 Mar;52 (1) :76-82.|[2]Umamaheshwari RB, et al., Receptor-mediated targeting of lipobeads bearing acetohydroxamic acid for eradication of Helicobacter pylori. J Control Release. 2004 Sep 14;99 (1) :27-40.|[3]Liu YH, et al., Antiglycation, radical scavenging, and semicarbazide-sensitive amine oxidase inhibitory activities of acetohydroxamic acid in vitro. Drug Des Devel Ther. 2017 Jul 13;11:2139-2147.
Shipping Conditions
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Scientific Category
Reference compound1
Clinical Information
Launched

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