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(S) -BRD9500

CAT: 0804-HY-136350B-01Size: 5 mgDry Ice: NoHazardous: No
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CAT#:0804-HY-136350B-01Size:5 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
(S) -BRD9500 is the isomer of BRD9500 , and can be used as an experimental control. BRD9500 is an orally active phosphodiesterases 3 (PDE3) inhibitor with IC50s of 10 and 27 nM for PDE3A and PDE3B, respectively. Antitumor activity[1].
CAS Number
1630760-76-7
UNSPSC
12352005
Hazard Statement
H302-H315-H319-H335
Target
Phosphodiesterase (PDE)
Type
Reference compound
Related Pathways
Metabolic Enzyme/Protease
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/s-brd9500.html
Purity
99.67
Solubility
DMSO : 200 mg/mL (ultrasonic)
Smiles
O=C1C[C@H](C)C(C2=CC=C(N3CCOCC3)C(F)=C2)=NN1
Molecular Formula
C15H18FN3O2
Molecular Weight
291.33
Precautions
P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501
References & Citations
[1]Timothy A Lewis, et al. Optimization of PDE3A Modulators for SLFN12-Dependent Cancer Cell Killing. ACS Med Chem Lett. 2019 Oct 18;10 (11) :1537-1542.
Shipping Conditions
Room Temperature
Storage Conditions
4°C (Powder, sealed storage, away from moisture)
Scientific Category
Reference compound1
Clinical Information
No Development Reported

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