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BIM-23027

CAT: 0804-HY-P3958-01Size: 1 mgDry Ice: NoHazardous: No
CAT#:0804-HY-P3958-01Size:1 mg
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AVAILABILITY: InStock
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
BIM-23027 is a selective agonist of sst2 receptor (EC50=0.32 nM), with similar effect to somatostatin (SRIF), a cyclic tetradecapeptide. BIM-23027 stimulates dopamine release, which is mediated by a Glu-dependent mechanism[1][2].
CAS Number
[78981-49-4]
UNSPSC
12352209
Target
Dopamine Receptor; Somatostatin Receptor
Type
Peptides
Related Pathways
GPCR/G Protein; Neuronal Signaling
Applications
Neuroscience-Neuromodulation
Field of Research
Neurological Disease
Assay Protocol
https://www.medchemexpress.com/bim-23027.html
Purity
99.76
Solubility
10 mM in DMSO
Smiles
O=C([C@@H](NC([C@@H](N(C([C@@H](NC([C@](NC([C@@H](NC1=O)CCCCN)=O)([H])[C@H](O)C)=O)CC2=CC=CC=C2)=O)C)C)=O)CC3=CC=CC=C3)N[C@@H]1CC4=CNC5=CC=CC=C45
Molecular Formula
C43H54N8O7
Molecular Weight
794.94
References & Citations
[1]Hathway GJ, et al. Evidence that somatostatin sst2 receptors mediate striatal dopamine release. Br J Pharmacol. 1999 Nov;128 (6) :1346-52. |[2]McKeen ES, et al. Somatostatin receptors mediating inhibition of basal and stimulated electrogenic ion transport in rat isolated distal colonic mucosa. Naunyn Schmiedebergs Arch Pharmacol. 1995 Oct;352 (4) :402-11.
Shipping Conditions
Blue Ice
Storage Conditions
-80°C, 2 years; -20°C, 1 year (Powder, sealed storage, away from moisture)
Scientific Category
Peptides
Clinical Information
No Development Reported

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