BIM-46068

• Description :

  BIM-46068 is a potent, selectively human brain Farnesyltransferase (FTase) inhibitor (IC50 = 91.4 nM) . BIM-46068 can specifically inhibit Ras processing in MiaPaCa-2 cancer cells. BIM-46068 can be used for the study of pancreatic cancer[1].

• UNSPSC :

  12352005

• Target :

  Farnesyl Transferase

• Related Pathways :

  Metabolic Enzyme/Protease

• Field of Research :

  Cancer

• Smiles :

  CSCC[C@@H](C(OC)=O)NC([C@H]1N(C[C@@H](NC[C@@H](N)CS)[C@@H](C)CC)CSC1(C)C)=O

• Molecular Formula :

  C21H42N4O3S3

• Molecular Weight :

  494.78

• References & Citations :

  [1]Prevost GP, et al. Inhibition of human tumor cell growth in vitro and in vivo by a specific inhibitor of human farnesyltransferase: BIM-46068. Int J Cancer. 1999 Oct 8;83 (2) :283-7.

• Shipping Conditions :

  Room temperature

• Scientific Category :

  Reference compound1

• Clinical Information :

  No Development Reported

• CAS Number :

  [201487-53-8]