(E/Z)-Icerguastat

(E/Z)-Icerguastat

• CAS Number: 13098-73-2
• UNSPSC Description: (E/Z)-Icerguastat ((E/Z)-Sephin1) is a selective inhibitor of the phosphatase regulatory subunit PPP1R15A (R15A). (E/Z)-Icerguastat can be used for protein misfolding diseases research[1].
• Target Antigen: Phosphatase
• Type: Reference compound
• Related Pathways: Metabolic Enzyme/Protease
• Applications: COVID-19-immunoregulation
• Field of Research: Inflammation/Immunology
• Assay Protocol: https://www.medchemexpress.com/e-z-icerguastat.html
• Purity: 99.44
• Solubility: DMSO : 100 mg/mL (ultrasonic)
• Smiles: ClC1=CC=CC=C1/C=N/NC(N)=N
• Molecular Weight: 196.64
• References & Citations: [1]Das I, et al. Preventing proteostasis diseases by selective inhibition of a phosphatase regulatory subunit. Science. 2015 Apr 10;348(6231):239-42.
• Shipping Conditions: Room Temperature
• Storage Conditions: -20°C, 3 years; 4°C, 2 years (Powder)
• Clinical Information: No Development Reported