Glucokinase

• Description:

  Glucokinase is a glucose-phosphorylating enzyme that has an important role in glucose homeostasis. Glucokinase acts as a glucose sensot of pancreatic β-cells. Glucokinase regulates the conversion of glucose to glucogen as well as gluconeogenesis. Glucokinase in mammals can phosphorylate hexoses like mannose or fructose in addition to glucose. Glucokinase can be studied in research on diabetes[1][2].

• UNSPSC:

  12352204

• Target:

  Biochemical Assay Reagents

• Type:

  Enzyme

• Related Pathways:

  Others

• Field of Research:

  Metabolic Disease

• Assay Protocol:

  https://www.medchemexpress.com/glucokinase.html

• Solubility:

  H2O : ≥ 50 mg/mL

• Smiles:

  [Glucokinase]

• References & Citations:

  [1]Matschinsky F. M. (2009) . Assessing the potential of glucokinase activators in diabetes therapy. Nature reviews. Drug discovery, 8 (5), 399-416. |[2]Iynedjian P. B. (2009) . Molecular physiology of mammalian glucokinase. Cellular and molecular life sciences : CMLS, 66 (1), 27-42.

• Shipping Conditions:

  Blue Ice

• Storage Conditions:

  Store at -20°C for 2 years

• Scientific Category:

  Enzyme

• Clinical Information:

  Phase 1

• CAS Number:

  [9001-36-9]