Enlicitide (chloride)

Enlicitide (chloride)

• CAS Number: 2407527-16-4
• UNSPSC Description: Enlicitide chloride is a potent PCSK9 antagonist. Enlicitide chloride can be used in the study of cardiovascular diseases such as atherosclerosis, hypercholesterolemia, coronary heart disease, metabolic syndrome, acute coronary syndrome or related cardiovascular and cardiometabolic disorders[1][2].
• Target Antigen: Ser/Thr Protease
• Type: Peptides
• Related Pathways: Metabolic Enzyme/Protease
• Applications: Neuroscience-Neuromodulation
• Field of Research: Cardiovascular Disease
• Assay Protocol: https://www.medchemexpress.com/enlicitide-chloride.html
• Purity: 98.74
• Solubility: DMSO : 1 mg/mL (ultrasonic;warming)
• Smiles: FC1=CC=C2C(C(C[C@@](NC([C@](NC([C@H](NC([C@@H](N3)C)=O)CNC(CCCCC[N+](C)(C)C)=O)=O)([H])CC4=CC=CC5=C4)=O)([H])C(N6[C@@](C(N[C@@](C(N[C@H](C(N(CCC7)[C@@]78C)=O)CC(C=C9)=CC=C9OC)=O)([H])[C@H](O)C)=O)([H])[C@](OCC(NC5)=O)([H])CC6)=O)=CN2CCCCCCN(C(CCC3=O)=O)CC%10=CC=C(CCNC8=O)C=C%10)=C1.[Cl-]
• Molecular Weight: 1586.29
• References & Citations: [1]Ding FX, et al. Preparation of cyclic peptides as PCSK9 antagonist compounds: World Intellectual Property Organization, WO2019246349. 2019-12-26.|[2]WHO Drug Information-World Health Organization (WHO).
• Shipping Conditions: Blue Ice
• Storage Conditions: -80°C, 2 years; -20°C, 1 year (Powder, sealed storage, away from moisture)
• Clinical Information: No Development Reported