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Tesmilifene

CAT: 0804-HY-13762Size: 1 EachDry Ice: NoHazardous: No
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CAT#:0804-HY-13762Size:1 Each
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
Tesmilifene is an antihistamine agent and a chemical sensitizer. Tesmilifene targets cytochrome P450, exhibits hormonal effects on DNA synthesis in MCF-7 cells, and stimulates the tumor growth in mouse/rat models. Tesmilifene overcomes multidrug resistance[1].
CAS Number
98774-23-3
UNSPSC
12352005
Hazard Statement
H302-H315-H319-H335
Target
Cytochrome P450
Type
Reference compound
Related Pathways
Metabolic Enzyme/Protease
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/tesmilifene.html
Smiles
CCN(CC)CCOC1=CC=C(CC2=CC=CC=C2)C=C1
Molecular Formula
C19H25NO
Molecular Weight
283.41
Precautions
P261-P264-P270-P271-P280-P302+P352-P304+P340-P330-P362+P364-P405-P501
References & Citations
[1]Brandes LJ. N, N-diethyl-2-[4- (phenylmethyl) phenoxy] ethanamine (DPPE; tesmilifene), a chemopotentiating agent with hormetic effects on DNA synthesis in vitro, may improve survival in patients with metastatic breast cancer. Hum Exp Toxicol. 2008 Feb;27 (2) :143-7.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
Phase 2

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