AKR1C3-IN-12
CAT:
804-HY-163323
Size:
Inquire
Price:
Ask
- Availability: 24/48H Stock Items & 2 to 6 Weeks non Stock Items.
- Dry Ice Shipment: No
AKR1C3-IN-12
- CAS Number: 891075-67-5
- UNSPSC Description: AKR1C3-IN-12 (compound 2j) is an aldo-keto reductase 1C3 (AKR1C3) inhibitor with an IC50 of 27 nM. AKR1C3-IN-12 enhances the efficacy of Gemcitabine and Cisplatin in bladder cancer[1].
- Target Antigen: Aldose Reductase
- Type: Reference compound
- Related Pathways: Metabolic Enzyme/Protease
- Applications: Cancer-programmed cell death
- Field of Research: Cancer
- Assay Protocol: https://www.medchemexpress.com/akr1c3-in-12.html
- Solubility: 10 mM in DMSO
- Smiles: O=C(C1=CC2=C(OC1=N)C(O)=CC=C2)NC3=CC=C(C)C=C3
- Molecular Weight: 294.30
- References & Citations: [1]Rin Himura, et al. Inhibition of aldo-keto reductase 1C3 overcomes gemcitabine/cisplatin resistance in bladder cancer. Chem Biol Interact. 2024 Jan 25:388:110840.
- Shipping Conditions: Room temperature
- Clinical Information: No Development Reported