AKR1C3-IN-9
CAT:
804-HY-152188-01
Size:
25 mg
Price:
Ask
- Availability: 24/48H Stock Items & 2 to 6 Weeks non Stock Items.
- Dry Ice Shipment: No
AKR1C3-IN-9
- CAS Number: 2924824-43-9
- UNSPSC Description: AKR1C3-IN-9 is a selective inhibitor of Aldo-keto Reductase 1C3 (AKR1C3) with an IC50 value of 8.92 nM. AKR1C3-IN-9 significantly reverses the Doxorubicin (HY-15142A) (DOX) resistance in a resistant breast cancer cell line[1].
- Target Antigen: Aldose Reductase
- Type: Reference compound
- Related Pathways: Metabolic Enzyme/Protease
- Applications: Cancer-programmed cell death
- Field of Research: Cancer
- Assay Protocol: https://www.medchemexpress.com/akr1c3-in-9.html
- Solubility: DMSO : 83.33 mg/mL (ultrasonic;warming;heat to 60°C)
- Smiles: COC1=CC=CC=C1NC(C2=CC=CC=C2OCC3=C(ON=C3C)C)=O
- Molecular Weight: 352.38
- References & Citations: [1]Liu Y, et al. Development of highly potent and specific AKR1C3 inhibitors to restore the chemosensitivity of drug-resistant breast cancer. Eur J Med Chem. 2022 Dec 13;247:115013.
- Shipping Conditions: Blue Ice
- Clinical Information: No Development Reported