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Hydroxycitric acid

CAT: 0804-HY-N1437-01Size: 50 mgDry Ice: NoHazardous: No
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CAT#:0804-HY-N1437-01Size:50 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
Hydroxycitric acid is the major active ingredient of Garcinia cambogia. Hydroxycitric acid competitively inhibits ATP citrate lyase with weight loss benefits. Hydroxycitric acid effective inhibits stones formation and also inhibits HIF, and has antioxidation, anti-inflammation and anti-tumor effects[1][2][3][4].
CAS Number
6205-14-7
UNSPSC
12352211
Hazard Statement
H302, H315, H319, H335
Target
ATP Citrate Lyase; HIF/HIF Prolyl-Hydroxylase
Type
Natural Products
Related Pathways
Metabolic Enzyme/Protease
Applications
Metabolism-protein/nucleotide metabolism
Field of Research
Cancer; Metabolic Disease; Inflammation/Immunology
Assay Protocol
https://www.medchemexpress.com/hydroxycitric-acid-1.html
Purity
98.79
Solubility
10 mM in DMSO
Smiles
OC(C(C(O)=O)O)(C(O)=O)CC(O)=O
Molecular Formula
C6H8O8
Molecular Weight
208.12
Precautions
H302, H315, H319, H335
References & Citations
[1]Liu X, et al. Hydroxycitric acid inhibits renal calcium oxalate deposition by reducing oxidative stress and inflammation. Curr Mol Med. 2020 Jan 3. |[2]Ibuki M, et al. Therapeutic Effect of Garcinia cambogia Extract and Hydroxycitric Acid Inhibiting Hypoxia-Inducible Factor in a Murine Model of Age-Related Macular Degeneration. Int J Mol Sci. 2019 Oct 11;20 (20) . pii: E5049.|[3]Han S, et al. Hydroxycitric Acid Tripotassium Inhibits Calcium Oxalate Crystal Formation in the Drosophila Melanogaster Model of Hyperoxaluria. Med Sci Monit. 2019 May 17;25:3662-3667.|[4]Heymsfield SB, et al. Garcinia cambogia (hydroxycitric acid) as a potential antiobesity agent: a randomized controlled trial. JAMA. 1998 Nov 11;280 (18) :1596-600.
Shipping Conditions
Blue Ice
Storage Conditions
-20°C, 3 years (Powder)
Scientific Category
Natural Products
Clinical Information
No Development Reported

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