Kahweol (Standard)

• UNSPSC Description:

  Kahweol (Standard) is the analytical standard of Kahweol. This product is intended for research and analytical applications. Kahweol is one of the consituents of the coffee from Coffea Arabica with anti-inflammatory anti-angiogenic, and anti-cancerous activities. Kahweol inhibits adipogenesis and increase glucose uptake by AMP-activated protein kinase (AMPK) activation. Kahweol induces apoptosis.

• Target Antigen:

  AMPK; Apoptosis

• Type:

  Reference Standards

• Related Pathways:

  Apoptosis;Epigenetics;PI3K/Akt/mTOR

• Field of Research:

  Metabolic Disease

• Assay Protocol:

  https://www.medchemexpress.com/kahweol-standard.html

• Smiles:

  C[C@]12[C@@]3([H])[C@@]4(CC[C@]1([H])C5=C(OC=C5)C=C2)C[C@@]([C@](CO)(O)C4)([H])CC3

• Molecular Weight:

  314.42

• References & Citations:

  [1]Seo HY, et al. Kahweol decreases hepatic fibrosis by inhibiting the expression of connective tissue growth factor via the transforming growth factor-beta signaling pathway. Oncotarget. 2017 Aug 1;8(50):87086-87094.|[2]Baek JH, et al. Kahweol inhibits lipid accumulation and induces Glucose-uptake through activation of AMP-activated protein kinase (AMPK). BMB Rep. 2017 Nov;50(11):566-571.

• Shipping Conditions:

  Room temperature

• CAS Number:

  6894-43-5