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Riociguat (Standard)

CAT: 0804-HY-14779R-01Size: 5 mgDry Ice: NoHazardous: No
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CAT#:0804-HY-14779R-01Size:5 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
Riociguat (Standard) is the analytical standard of Riociguat. This product is intended for research and analytical applications. Riociguat is an oral stimulator of soluble guanylate cyclase (sGC) used in the treatment of pulmonary hypertension.
CAS Number
625115-55-1
Product Name Alternative
BAY 632521 (Standard)
UNSPSC
12352005
Hazard Statement
H301-H361-H410
Target
Guanylate Cyclase; Reference Standards
Type
Reference Standards
Related Pathways
GPCR/G Protein; Others
Field of Research
Cardiovascular Disease
Assay Protocol
https://www.medchemexpress.com/riociguat-standard.html
Smiles
FC1=CC=CC=C1CN2C3=NC=CC=C3C(C4=NC(N)=C(C(N)=N4)N(C)C(OC)=O)=N2
Molecular Formula
C20H19FN8O2
Molecular Weight
422.42
Precautions
P264-P270-P273-P280-P391-P405-P501
References & Citations
[1]Schermuly RT, et al. Expression and function of soluble guanylate cyclase in pulmonary arterial hypertension. Eur Respir J. 2008 Oct;32 (4) :881-91.|[2]Schermuly RT, et al. Riociguat for the treatment of pulmonary hypertension. Expert Opin Investig Drugs. 2011 Apr;20 (4) :567-76.|[3]Donda K, et al. Riociguat prevents hyperoxia-induced lung injury and pulmonary hypertension in neonatal rats without effects on long bone growth. PLoS One. 2018 Jul 10;13 (7) :e0199927.
Shipping Conditions
Room temperature
Scientific Category
Reference Standards

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