5-Methylcytidine 5′-triphosphate-d8 (trisodium)

• UNSPSC Description:

  5-Methylcytidine 5'-triphosphate-d8 trisodium is the deuterium-labeled form of 5-Methylcytidine 5'-triphosphate trisodium (HY-147338A). 5-Methylcytidine 5'-triphosphate (5-Methyl-CTP) trisodium is a modified nucleoside triphosphate. 5-Methylcytidine 5'-triphosphate trisodium can be used to replace unmodified mRNA, resulting in the increase of translational properties and stability, as well as the reduction of innate immune responses in human and other mammalian cells[1].

• Target Antigen:

  Isotope-Labeled Compounds

• Type:

  Isotope-Labeled Compounds

• Related Pathways:

  Others

• Field of Research:

  Inflammation/Immunology

• Smiles:

  O=P(OP(OP(O[2H])(O[Na])=O)(O[Na])=O)(O[Na])OC[C@@H]1[C@@H](O[2H])[C@@H](O[2H])[C@H](N2C(N=C(N([2H])[2H])C(C([2H])([2H])[2H])=C2)=O)O1

• Molecular Weight:

  571.18

• References & Citations:

  [1]Shanmugasundaram M, et al. An Efficient Protection-Free One-Pot Chemical Synthesis of Modified Nucleoside-5'-Triphosphates. Nucleosides Nucleotides Nucleic Acids. 2016 Jul 2;35(7):356-62.|[2]Shanmugasundaram M, et al. An Efficient Protection-Free One-Pot Chemical Synthesis of Modified Nucleoside-5'-Triphosphates. Nucleosides Nucleotides Nucleic Acids. 2016 Jul 2;35(7):356-62.

• Shipping Conditions:

  Room temperature

• Clinical Information:

  No Development Reported