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Donanemab

CAT: 0804-HY-P99859-01Size: 1 mgDry Ice: YesHazardous: No
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CAT#:0804-HY-P99859-01Size:1 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
Donanemab (LY3002813) is a humanized IgG1 monoclonal antibody directed at an N-terminal pyroglutamate amyloid beta (Aβ) epitope. Donanemab has the potential for early Alzheimer's disease research[1][2].
CAS Number
1931944-80-7
Product Name Alternative
LY3002813
UNSPSC
12352203
Target
Amyloid-β
Type
Inhibitory Antibodies
Related Pathways
Neuronal Signaling
Applications
Neuroscience-Neurodegeneration
Field of Research
Neurological Disease
Assay Protocol
https://www.medchemexpress.com/donanemab.html
Purity
99.19
Solubility
10 mM in DMSO
Smiles
[Donanemab]
Molecular Weight
(145.36 kDa)
References & Citations
[1]Stephen Loucian Lowe, et al. Donanemab (LY3002813) dose-escalation study in Alzheimer's disease. Alzheimers Dement (N Y) . 2021 Feb 14;7 (1) :e12112.|[2]Mark A Mintun, et al. Donanemab in Early Alzheimer's Disease. N Engl J Med. 2021 May 6;384 (18) :1691-1704.
Shipping Conditions
Dry Ice
Storage Conditions
Store at -80°C for 2 years
Scientific Category
Inhibitory Antibodies
Clinical Information
Launched

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