Citral

• UNSPSC Description:

  Citral is an orally active monoterpene compound in lemon grass essential oil and a natural ALDH1A inhibitor, which can induce apoptosis and cycle arrest in breast cancer cell lines, and has analgesic, anti-injurious and anti-inflammatory effects[2][3].

• Target Antigen:

  Aldehyde Dehydrogenase (ALDH); Apoptosis

• Type:

  Natural Products

• Related Pathways:

  Apoptosis;Metabolic Enzyme/Protease

• Applications:

  COVID-19-immunoregulation

• Field of Research:

  Inflammation/Immunology; Cancer

• Assay Protocol:

  https://www.medchemexpress.com/citral.html

• Purity:

  97.0

• Solubility:

  DMSO : 50 mg/mL (ultrasonic)|H2O : 1 mg/mL (ultrasonic;warming;heat to 80°C)

• Smiles:

  C/C(C)=C\CC/C(C)=C/C=O

• Molecular Weight:

  152.23

• References & Citations:

  [1]Campos CA, et al. Anti-hyperalgesic and anti-inflammatory effects of citral with β-cyclodextrin and hydroxypropyl-β-cyclodextrin inclusion complexes in animal models. Life Sci. 2019 Jul 15;229:139-148. |[2]Chaouki W, et al. Citral inhibits cell proliferation and induces apoptosis and cell cycle arrest in MCF-7 cells. Fundam Clin Pharmacol. 2009 Oct;23(5):549-56. |[3]Souza ACS, et al. Citral presents cytotoxic and genotoxic effects in human cultured cells. Drug Chem Toxicol. 2020 Jul;43(4):435-440. |[4]Zhao W, et al. Citral protects against LPS-induced endometritis by inhibiting ferroptosis through activating Nrf2 signaling pathway. Inflammopharmacology. 2023 Jun;31(3):1551-1558.

• Shipping Conditions:

  Room Temperature

• Storage Conditions:

  -20°C, 3 years (Powder)

• Clinical Information:

  No Development Reported

• CAS Number:

  5392-40-5