Sodium taurodeoxycholate (Highly Pure)

• Description:

  Sodium taurodeoxycholate (Highly Pure)_x000D_ Catalog number: B2010638_x000D_ Lot number: Batch Dependent_x000D_ Expiration Date: Batch dependent_x000D_ Amount: 1 g_x000D_ Molecular Weight or Concentration: 521.69 g/mol_x000D_ Supplied as: Powder_x000D_ Applications: molecular tool in the study of various metabolic systems_x000D_ Storage: RT_x000D_ Keywords: 2-([3α,12α-Dihydroxy-24-oxo-5β-cholan-24-yl]amino)ethanesulfonic acid, Taurodeoxycholic acid sodium salt hydrate_x000D_ Grade: Biotechnology grade. All products are highly pure. All solutions are made with Type I ultrapure water (resistivity >18 MΩ-cm) and are filtered through 0.22 um._x000D_ _x000D_ References:_x000D_ 1: Paganoni S, Macklin EA, Hendrix S, Berry JD, Elliott MA, Maiser S, Karam C,_x000D_ Caress JB, Owegi MA, Quick A, Wymer J, Goutman SA, Heitzman D, Heiman-Patterson_x000D_ T, Jackson CE, Quinn C, Rothstein JD, Kasarskis EJ, Katz J, Jenkins L, Ladha S,_x000D_ Miller TM, Scelsa SN, Vu TH, Fournier CN, Glass JD, Johnson KM, Swenson A, Goyal_x000D_ NA, Pattee GL, Andres PL, Babu S, Chase M, Dagostino D, Dickson SP, Ellison N,_x000D_ Hall M, Hendrix K, Kittle G, McGovern M, Ostrow J, Pothier L, Randall R, Shefner_x000D_ JM, Sherman AV, Tustison E, Vigneswaran P, Walker J, Yu H, Chan J, Wittes J,_x000D_ Cohen J, Klee J, Leslie K, Tanzi RE, Gilbert W, Yeramian PD, Schoenfeld D,_x000D_ Cudkowicz ME. Trial of Sodium Phenylbutyrate-Taurursodiol for Amyotrophic_x000D_ Lateral Sclerosis. N Engl J Med. 2020 Sep 3;383(10):919-930._x000D_ _x000D_ 2: Choi HJ, Yun JW, Kim YH, Kwon E, Hyon MK, Kim JY, Che JH, Park JS, Kim HC, Ho_x000D_ Kim W, Seong SY, Kang BC. Nonclinical toxicology studies with sodium_x000D_ taurodeoxycholate: acute and subacute toxicity in dogs. Drug Chem Toxicol. 2021_x000D_ Mar;44(2):161-169._x000D_ _x000D_ 3: Pardue MT, Allen RS. Neuroprotective strategies for retinal disease. Prog_x000D_ Retin Eye Res. 2018 Jul;65:50-76._x000D_ _x000D_ 4: Choi HJ, Yun JW, Kim YH, Kwon E, Hyon MK, Kim JY, Che JH, Ho Kim W, Seong SY,_x000D_ Kang BC. Evaluation of acute and subacute toxicity of sodium taurodeoxycholate_x000D_ in rats. Drug Chem Toxicol. 2021 May;44(3):268-276._x000D_ _x000D_ 5: Kusaczuk M. Tauroursodeoxycholate-Bile Acid with Chaperoning Activity:_x000D_ Molecular and Cellular Effects and Therapeutic Perspectives. Cells. 2019 Nov_x000D_ 20;8(12):1471._x000D_ _x000D_ 6: Bhargava P, Smith MD, Mische L, Harrington E, Fitzgerald KC, Martin K, Kim S,_x000D_ Reyes AA, Gonzalez-Cardona J, Volsko C, Tripathi A, Singh S, Varanasi K, Lord_x000D_ HN, Meyers K, Taylor M, Gharagozloo M, Sotirchos ES, Nourbakhsh B, Dutta R,_x000D_ Mowry EM, Waubant E, Calabresi PA. Bile acid metabolism is altered in multiple_x000D_ sclerosis and supplementation ameliorates neuroinflammation. J Clin Invest. 2020_x000D_ Jul 1;130(7):3467-3482._x000D_ _x000D_ 7: Elia AE, Lalli S, Monsurrò MR, Sagnelli A, Taiello AC, Reggiori B, La Bella_x000D_ V, Tedeschi G, Albanese A. Tauroursodeoxycholic acid in the treatment of_x000D_ patients with amyotrophic lateral sclerosis. Eur J Neurol. 2016 Jan;23(1):45-52._x000D_ doi: 10.1111/ene.12664. Epub 2015 Feb 9. Erratum in: Eur J Neurol. 2017_x000D_ Apr;24(4):659._x000D_ _x000D_ 8: Kobayashi T, Suzuki K. A taurodeoxycholate-activated galactosylceramidase in_x000D_ the murine intestine. J Biol Chem. 1981 Feb 10;256(3):1133-7._x000D_ _x000D_ 9: Enache M, Toader AM, Neacsu V, Ionita G, Enache MI. Spectroscopic_x000D_ Investigation of the Interaction of the Anticancer Drug Mitoxantrone with Sodium_x000D_ Taurodeoxycholate (NaTDC) and Sodium Taurocholate (NaTC) Bile Salts. Molecules._x000D_ 2017 Jun 28;22(7):1079._x000D_ 10: Chang S, Kim YH, Kim YJ, Kim YW, Moon S, Lee YY, Jung JS, Kim Y, Jung HE,_x000D_ Kim TJ, Cheong TC, Moon HJ, Cho JA, Kim HR, Han D, Na Y, Seok SH, Cho NH, Lee_x000D_ HC, Nam EH, Cho H, Choi M, Minato N, Seong SY. Taurodeoxycholate Increases the_x000D_ Number of Myeloid-Derived Suppressor Cells That Ameliorate Sepsis in Mice. Front_x000D_ Immunol. 2018 Sep 18;9:1984._x000D_ _x000D_ Products Related to Sodium taurodeoxycholate (Highly Pure): Chemicals

• Short Description:

  Catalog Number: B2010638 (1 g)

• Weight:

  0.8

• Length:

  2

• Width:

  0.9

• Height:

  0.9

• Height :

  0.9