DOTAP (chloride)
CAT:
804-HY-112754A-02
Size:
10 mM / 1 mL
Price:
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- Availability: 24/48H Stock Items & 2 to 6 Weeks non Stock Items.
- Dry Ice Shipment: No
DOTAP (chloride)
- CAS Number: 132172-61-3
- UNSPSC Description: DOTAP chloride is a useful and effective cationic lipid for transient and stable transfection DNA (plasmids, bacmids) and modified nucleic acids (antisense oligonucleotides) with out the use of helper lipid[1].
- Target Antigen: Liposome
- Type: Oligonucleotides
- Related Pathways: Metabolic Enzyme/Protease
- Field of Research: Cancer
- Assay Protocol: https://www.medchemexpress.com/dotap-chloride.html
- Purity: 98.0
- Solubility: DMSO : 25 mg/mL (ultrasonic;warming;heat to 60°C)|Ethanol : 130 mg/mL (ultrasonic)
- Smiles: CCCCCCCC/C=C\CCCCCCCC(OCC(OC(CCCCCCC/C=C\CCCCCCCC)=O)C[N+](C)(C)C)=O.[Cl-]
- Molecular Weight: 698.54
- References & Citations: [1]Kim BK, et al. DOTAP/DOPE ratio and cell type determine transfection efficiency with DOTAP-liposomes.Biochim Biophys Acta. 2015 Oct;1848(10 Pt A):1996-2001.Adv Healthc Mater. 2022: 2202412.|Exploration. 2024 Jun 26.|Nanoscale. 2023 Nov 16;15(44):17825-17838.|Pharmaceutics. 2023 Apr 30, 15(5), 1379.|SSRN. 2024 Nov 12.|Drug Dev Ind Pharm. 2024 Aug 7:1-16.
- Shipping Conditions: Blue Ice
- Storage Conditions: -20°C (Powder, protect from light, stored under nitrogen)
- Clinical Information: Phase 2