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Lanatoside C

CAT: 0804-HY-B1030-01Size: 5 mgDry Ice: NoHazardous: No
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CAT#:0804-HY-B1030-01Size:5 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
Lanatoside C is a cardiac glycoside, can be used in the treatment of congestive heart failure and cardiac arrhythmia.Lanatoside C has an IC50 of 0.19 μM for dengue virus infection in HuH-7 cells. Lanatoside C can effectively inhibit all four serotypes of dengue virus, flavivirus Kunjin, alphavirus Chikungunya, Sindbis virus and the human enterovirus 71[1][2].
CAS Number
17575-22-3
UNSPSC
12352005
Hazard Statement
H301, H330, H373
Target
Autophagy; CHIKV; Dengue Virus; Enterovirus; Flavivirus
Type
Natural Products
Related Pathways
Anti-infection; Autophagy
Applications
COVID-19-anti-virus
Field of Research
Cardiovascular Disease; Cancer
Assay Protocol
https://www.medchemexpress.com/Lanatoside-C.html
Purity
99.88
Solubility
DMSO : 50 mg/mL (ultrasonic) |Ethanol : 2 mg/mL (ultrasonic)
Smiles
O[C@]([C@@](CC[C@@]1([H])[C@@]2(CC[C@H](O[C@@](O[C@H](C)[C@H]3O[C@@](O[C@H](C)[C@H]4O[C@@](O[C@H](C)[C@H]5O[C@]([C@@H]([C@@H](O)[C@@H]6O)O)([H])O[C@@H]6CO)([H])C[C@@H]5OC(C)=O)([H])C[C@@H]4O)([H])C[C@@H]3O)C1)C)([H])[C@]2([H])C[C@H]7O)(CC[C@@H]8C(CO9)=CC9=O)[C@]78C
Molecular Formula
C49H76O20
Molecular Weight
985.12
Precautions
H301, H330, H373
References & Citations
[1]Crommentuijn MH, et al. Intracranial AAV-sTRAIL combined with lanatoside C prolongs survival in an orthotopic xenograft mouse model of invasive glioblastoma. Mol Oncol. 2015 Dec 11. pii: S1574-7891 (15) 00226-4.|[2]Cheung YY, et al. Antiviral activity of lanatoside C against dengue virus infection. Antiviral Res. 2014 Nov;111:93-99.
Shipping Conditions
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Scientific Category
Natural Products
Clinical Information
Launched

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