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Risarestat

CAT: 0804-HY-16433-02Size: 10 mM - 1 mLDry Ice: NoHazardous: No
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CAT#:0804-HY-16433-02Size:10 mM - 1 mL
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
Risarestat (CT-112), an aldose reductase inhibitor, is developed for the treatment of diabetic complications.
CAS Number
79714-31-1
Product Name Alternative
CT 112
UNSPSC
12352005
Target
Aldose Reductase
Type
Reference compound
Related Pathways
Metabolic Enzyme/Protease
Applications
Metabolism-sugar/lipid metabolism
Field of Research
Metabolic Disease; Inflammation/Immunology
Assay Protocol
https://www.medchemexpress.com/RISARESTAT.html
Purity
98.03
Solubility
DMSO : 105 mg/mL (ultrasonic)
Smiles
O=C(N1)SC(C2=CC=C(OCCCCC)C(OCC)=C2)C1=O
Molecular Formula
C16H21NO4S
Molecular Weight
323.41
References & Citations
[1]Awata T, et al. Effect of an aldose reductase inhibitor, CT-112, on healing of the corneal epithelium in galactose-fed rats. J Ocul Pharmacol. 1988 Fall;4 (3) :195-201.|[2]Ohashi Y, et al. Intraocular penetration of CT-112, an aldose reductase inhibitor, following topical instillation. J Ocul Pharmacol. 1989 Winter;5 (4) :325-8.|[3]Hosotani H, et al. Reversal of abnormal corneal epithelial cell morphologic characteristics and reduced corneal sensitivity in diabetic patients by aldose reductase inhibitor, CT-112. Am J Ophthalmol. 1995 Mar;119 (3) :288-94.|[4]Jacot JL, et al. Diabetic-like corneal sensitivity loss in galactose-fed rats ameliorated with aldose reductase inhibitors. J Ocul Pharmacol Ther. 1998 Apr;14 (2) :169-80.
Shipping Conditions
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Scientific Category
Reference compound1
Clinical Information
No Development Reported

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