Products for Research Use Only
RegisterLogin

Dodecanedioic acid

CAT: 0804-HY-W012241-02Size: 10 mM - 1 mLDry Ice: NoHazardous: No
Product image 1
1 / 1
CAT#:0804-HY-W012241-02Size:10 mM - 1 mL
Selected
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
Quick Request Actions
Description
Dodecanedioic acid is an orally active straight-chain dicarboxylic acid. As an alternative energy substrate between lipids and carbohydrates, Dodecanedioic acid can be rapidly oxidized during exercise, reducing muscle fatigue without stimulating insulin secretion. Dodecanedioic acid also exhibits blood glucose-lowering activity in non-insulin-dependent diabetes mellitus[1][2][3].
CAS Number
693-23-2
UNSPSC
12352211
Hazard Statement
H302, H315, H319, H335
Target
Endogenous Metabolite
Type
Natural Products
Related Pathways
Metabolic Enzyme/Protease
Applications
Metabolism-sugar/lipid metabolism
Field of Research
Metabolic Disease
Assay Protocol
https://www.medchemexpress.com/Dodecanedioic_acid.html
Purity
98.0
Solubility
DMSO : 100 mg/mL (ultrasonic) |H2O : < 0.1 mg/mL (ultrasonic)
Smiles
OC(=O)CCCCCCCCCCC(O)=O
Molecular Formula
C12H22O4
Molecular Weight
230.30
Precautions
H302, H315, H319, H335
References & Citations
[1]Greco AV, et al. The metabolic effect of dodecanedioic acid infusion in non-insulin-dependent diabetic patients. Nutrition. 1998 Apr;14 (4) :351-7.|[2]Greco AV, et al. Uptake of dodecanedioic acid by isolated rat liver. Clin Chim Acta. 1997 Feb 17;258 (2) :209-18.|[3]Salinari S, et al. Dodecanedioic acid overcomes metabolic inflexibility in type 2 diabetic subjects. Am J Physiol Endocrinol Metab. 2006 Nov;291 (5) :E1051-8.
Shipping Conditions
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Scientific Category
Natural Products
Clinical Information
No Development Reported

Chemical Information

Dodecanedioic Acid

Dodecanedioic acid is an alpha,-dicarboxylic acid that is dodecane in which the methyl groups have been oxidised to the corresponding carboxylic acids. It has a role as an EC 1.1.1.1 (alcohol dehydrogenase) inhibitor and a human metabolite. It is a dicarboxylic fatty acid and an alpha,omega-dicarboxylic acid. It is a conjugate acid of a dodecanedioate(2-). It derives from a hydride of a dodecane.

CAS Number693-23-2
PubChem CID12736
IUPAC Namedodecanedioic acid
Molecular FormulaC12H22O4
Molecular Weight230.30
XLogP3.2
Topological Polar Surface Area74.6
Hydrogen Bond Donor Count2
Hydrogen Bond Acceptor Count4
Rotatable Bond Count11
Heavy Atom Count16
Formal Charge0
Complexity179
SMILES
C(CCCCCC(=O)O)CCCCC(=O)O
InChI
InChI=1S/C12H22O4/c13-11(14)9-7-5-3-1-2-4-6-8-10-12(15)16/h1-10H2,(H,13,14)(H,15,16)
InChIKey
TVIDDXQYHWJXFK-UHFFFAOYSA-N
Chemical Structure
2D Structure
2D structure of Dodecanedioic Acid
CAS: 693-23-2
CID: 12736
Formula: C12H22O4
MW: 230.30
Interactive 3D Structure
Loading 3D structure...
View on PubChemRaw 3D data
Computed Properties
PropertyValue
Molecular Weight230.30
XLogP33.2
Hydrogen Bond Donor Count2
Hydrogen Bond Acceptor Count4
Rotatable Bond Count11
Exact Mass230.15180918
Monoisotopic Mass230.15180918
Topological Polar Surface Area74.6 Ų
Heavy Atom Count16
Formal Charge0
Complexity179
Isotope Atom Count0
Defined Atom Stereocenter Count0
Undefined Atom Stereocenter Count0
Defined Bond Stereocenter Count0
Undefined Bond Stereocenter Count0
Covalently-Bonded Unit Count1
Compound Is CanonicalizedYes

Related Products

CatalogName
HY-140112-01Acid-PEG2-SS-PEG2-acid
HY-140113-01Acid-PEG3-SS-PEG3-acid
HY-140589Acid-PEG4-S-PEG4-acid
HY-W087964-01Dodecanedioyl dichloride
HY-W096114-01Acid-PEG8-S-S-PEG8-acid
HY-140114-01Acid-PEG4-S-S-PEG4-acid
HY-W517110-01Deltamethric acid
HY-W342979-01Petroselaidic acid
HY-W004260-01Arachidic acid
HY-N0787-01Cryptochlorogenic acid

Alternative Products

CatalogName
MBS392445-01Dodecanedioic Acid
TRC-D494532-1MGDodecanedioic Acid-13C12
TRC-D494533-50MGDodecanedioic-d20 Acid
T5258-01Dodecanedioic acid diammonium salt
OR313077-01Dodecanedioic acid monomethyl ester
OR1043445-01Dodecanedioic acid diethyl ester

Popular Products