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BRD5080

CAT: 0804-HY-162735-01Size: 5 mgDry Ice: NoHazardous: No
CAT#:0804-HY-162735-01Size:5 mg
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AVAILABILITY: InStock
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
BRD5080 is a potent GPR65 positive allosteric modulator. BRD5080 induces GPR65-dependent cAMP production. BRD5080 exhibits a robust induction of cAMP activity and recruits G protein for the WT and variant hGPR65 as well as for the mouse ortholog. BRD5080 has the potential for autoimmune and inflammatory diseases research[1].
UNSPSC
12352101
Target
Others
Type
Reference compound
Related Pathways
Others
Applications
COVID-19-immunoregulation
Field of Research
Inflammation/Immunology
Assay Protocol
https://www.medchemexpress.com/brd5080.html
Purity
99.44
Smiles
O=C1C=C(C2=CC=C(COC(C)C)C=C2)NC3=C(C(NC4=C(F)C=C(C)C=C4)=O)C=NN31
Molecular Formula
C24H23FN4O3
Molecular Weight
434.46
References & Citations
[1]Ilona Neale, et al. Small-molecule probe for IBD risk variant GPR65 I231L alters cytokine signaling networks through positive allosteric modulation. Sci Adv. 2024 Jul 19;10 (29) :eadn2339.
Shipping Conditions
Blue Ice
Storage Conditions
-20°C, 3 years (Powder)
Scientific Category
Reference compound1
Clinical Information
No Development Reported

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