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L-162313

CAT: 0804-HY-112824-01Size: 1 mgDry Ice: NoHazardous: No
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CAT#:0804-HY-112824-01Size:1 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
L-162313 is a non-peptide angiotensin II AT1 and AT2 receptor agonist, with IC50 values of 1.1 and 2.0 nM for AT1 and AT2 receptor, respectively. L-162313 can be used for the research of vasoconstriction, aldosterone release, and cardiovascular growth[1].
CAS Number
151488-11-8
UNSPSC
12352005
Hazard Statement
H302, H315, H319
Target
Angiotensin Receptor
Type
Reference compound
Related Pathways
GPCR/G Protein
Applications
Neuroscience-Neuromodulation
Field of Research
Cardiovascular Disease
Assay Protocol
https://www.medchemexpress.com/l-162313.html
Purity
98.51
Solubility
DMSO : 100 mg/mL (ultrasonic)
Smiles
O=C(NS(=O)(C1=C(C2=CC=C(CN3C4=NC(C)=CC(C)=C4N=C3CC)C=C2)C=C(CC(C)C)S1)=O)OCCCC
Molecular Formula
C30H38N4O4S2
Molecular Weight
582.78
Precautions
H302, H315, H319
References & Citations
[1]Wan Y, et al. First reported nonpeptide AT1 receptor agonist (L-162,313) acts as an AT2 receptor agonist in vivo. J Med Chem. 2004 Mar 11;47 (6) :1536-46.
Shipping Conditions
Blue Ice
Storage Conditions
-20°C, 3 years (Powder)
Scientific Category
Reference compound1
Clinical Information
No Development Reported

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