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Selfotel

CAT: 0804-HY-15086-01Size: 5 mgDry Ice: NoHazardous: No
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CAT#:0804-HY-15086-01Size:5 mg
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Description
Selfotel (CGS 19755) is a selective and competitive antagonist at N-methyl-D-aspartate (NMDA) -preferring receptor. CGS 19755 inhibits the binding of [3H]-3- (2-carboxypiperazin-4-yl) propyl-1-phosphonic acid to NMDA-type receptors with an IC50 of 50 nM[1][2].
CAS Number
110347-85-8
Product Name Alternative
CGS 19755
UNSPSC
12352005
Hazard Statement
H302, H315, H319, H335
Target
IGluR
Type
Reference compound
Related Pathways
Membrane Transporter/Ion Channel; Neuronal Signaling
Applications
Neuroscience-Neurodegeneration
Field of Research
Neurological Disease
Assay Protocol
https://www.medchemexpress.com/selfotel.html
Purity
99.67
Solubility
H2O : 10 mg/mL (ultrasonic)
Smiles
O=C([C@@H]1NCC[C@H](CP(O)(O)=O)C1)O
Molecular Formula
C7H14NO5P
Molecular Weight
223.16
Precautions
H302, H315, H319, H335
References & Citations
[1]D A Bennett, et al. Behavioral pharmacological profile of CGS 19755, a competitive antagonist at N-methyl-D-aspartate receptors. J Pharmacol Exp Ther. 1989 Aug;250 (2) :454-60.|[2]J Lehmann, et al. CGS 19755, a selective and competitive N-methyl-D-aspartate-type excitatory amino acid receptor antagonist. J Pharmacol Exp Ther. 1988 Jul;246 (1) :65-75.|[3]M A Pérez-Pinzón, et al. Correlation of CGS 19755 neuroprotection against in vitro excitotoxicity and focal cerebral ischemia. J Cereb Blood Flow Metab. 1995 Sep;15 (5) :865-76.
Shipping Conditions
Blue Ice
Storage Conditions
-20°C, 3 years (Powder)
Scientific Category
Reference compound1
Clinical Information
Phase 3

Alternative Products

CatalogName
326895Selfotel

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