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Suberic acid

CAT: 0804-HY-W015300-01Size: 5 gDry Ice: NoHazardous: No
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CAT#:0804-HY-W015300-01Size:5 g
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
Suberic acid (Octanedioic acid) is an orally active crystalline dibasic acid. Suberic acid activates the Akt signaling pathway and regulates the expression of molecules related to the TGF-β and MAPK signaling pathways. Suberic acid inhibits skin dryness[1][2].
CAS Number
505-48-6
Product Name Alternative
Octanedioic acid
UNSPSC
12352211
Hazard Statement
H302, H315, H319, H335
Target
Akt; Endogenous Metabolite; p38 MAPK; TGF-β Receptor
Type
Natural Products
Related Pathways
MAPK/ERK Pathway; Metabolic Enzyme/Protease; PI3K/Akt/mTOR; TGF-beta/Smad
Applications
Metabolism-sugar/lipid metabolism
Field of Research
Metabolic Disease
Assay Protocol
https://www.medchemexpress.com/Octanedioic_acid.html
Purity
98.0
Solubility
DMSO : 100 mg/mL (ultrasonic)
Smiles
C(C(O)=O)CCCCCC(O)=O
Molecular Formula
C8H14O4
Molecular Weight
174.20
Precautions
H302, H315, H319, H335
References & Citations
[1]Kang W, et al. Activation of OR10A3 by Suberic Acid Promotes Collagen Synthesis in UVB-Irradiated Dermal Fibroblasts via the cAMP-Akt Pathway. Cells. 2022 Dec 7;11 (24) :3961.|[2]Kang W, et al. Dietary Suberic Acid Protects Against UVB-Induced Skin Photoaging in Hairless Mice. Nutrients. 2019 Dec 4;11 (12) :2948.
Shipping Conditions
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Scientific Category
Natural Products
Clinical Information
No Development Reported
Isoform
Human Endogenous Metabolite

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