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DAPT (GMP)

CAT: 0804-HY-13027G-01Size: 10 mgDry Ice: NoHazardous: No
CAT#:0804-HY-13027G-01Size:10 mg
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AVAILABILITY: InStock
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Description
DAPT (GSI-IX) (GMP) is DAPT (HY-13027) produced by using GMP guidelines. GMP small molecules works appropriately as an auxiliary reagent for cell therapy manufacture. DAPT is a potent and orally active γ-secretase inhibitor[1][2].
CAS Number
[208255-80-5]
Product Name Alternative
GSI-IX (GMP)
UNSPSC
12352005
Hazard Statement
H302, H315, H319, H335
Target
γ-secretase
Type
GMP Small Molecules
Related Pathways
Neuronal Signaling; Stem Cell/Wnt
Applications
Neuroscience-Neurodegeneration
Field of Research
Cancer; Inflammation/Immunology; Neurological Disease
Assay Protocol
https://www.medchemexpress.com/dapt-gmp.html
Purity
99.3
Solubility
10 mM in DMSO
Smiles
FC1=CC(F)=CC(CC(N[C@H](C(N[C@H](C(OC(C)(C)C)=O)C2=CC=CC=C2)=O)C)=O)=C1
Molecular Formula
C23H26F2N2O4
Molecular Weight
432.46
Precautions
H302, H315, H319, H335
References & Citations
[1]Choi IY, et al. Concordant but Varied Phenotypes among Duchenne Muscular Dystrophy Patient-Specific Myoblasts Derived using a Human iPSC-Based Model. Cell Rep. 2016 Jun 7;15 (10) :2301-2312.|[2]Qi Y, et al. Combined small-molecule inhibition accelerates the derivation of functional cortical neurons from human pluripotent stem cells. Nat Biotechnol. 2017 Feb;35 (2) :154-163.
Shipping Conditions
Blue Ice
Storage Conditions
4°C, sealed storage, away from moisture
Scientific Category
GMP Small Molecules
Clinical Information
No Development Reported

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