Cy5-PEG3-azide

• Description:

  Cy5-PEG3-azide is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1]. Cy5-PEG3-azide is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups.

• UNSPSC:

  12171500

• Target:

  Fluorescent Dye

• Type:

  Dye Reagents

• Related Pathways:

  Others

• Applications:

  Cancer-programmed cell death

• Field of Research:

  Cancer

• Assay Protocol:

  https://www.medchemexpress.com/cy5-peg3-azide.html

• Purity:

  99.47

• Solubility:

  10 mM in DMSO

• Smiles:

  CC (C1=CC=CC=C1N/2C) (C) C2=C/C=C/C=C/C3=[N+] (CCCCCC (NCCOCCOCCOCCN=[N+]=[N-]) =O) C (C=CC=C4) =C4C3 (C) C.[Cl-]

• Molecular Formula:

  C40H55ClN6O4

• Molecular Weight:

  719.36

• References & Citations:

  [1]An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562

• Shipping Conditions:

  Blue Ice

• Storage Conditions:

  -20°C (Powder, protect from light)

• Scientific Category:

  Dye Reagents

• Clinical Information:

  No Development Reported

• Isoform:

  PEG Linkers