Cy5-PEG3-azide

• Description :

  Cy5-PEG3-azide is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1]. Cy5-PEG3-azide is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups.

• UNSPSC :

  12171500

• Target :

  Fluorescent Dye

• Type :

  Dye Reagents

• Related Pathways :

  Others

• Applications :

  Cancer-programmed cell death

• Field of Research :

  Cancer

• Assay Protocol :

  https://www.medchemexpress.com/cy5-peg3-azide.html

• Purity :

  99.47

• Solubility :

  10 mM in DMSO

• Smiles :

  CC(C1=CC=CC=C1N/2C)(C)C2=C/C=C/C=C/C3=[N+](CCCCCC(NCCOCCOCCOCCN=[N+]=[N-])=O)C(C=CC=C4)=C4C3(C)C.[Cl-]

• Molecular Formula :

  C40H55ClN6O4

• Molecular Weight :

  719.36

• References & Citations :

  [1]An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562

• Shipping Conditions :

  Blue Ice

• Storage Conditions :

  -20°C (Powder, protect from light)

• Scientific Category :

  Dye Reagents

• Clinical Information :

  No Development Reported

• Isoform :

  PEG Linkers