N-(Azide-PEG3)-N'-(PEG4-NHS ester)-Cy5

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804-HY-141048

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UNSPSC Description: N-(Azide-PEG3)-N'-(PEG4-NHS ester)-Cy5 is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1]. N-(Azide-PEG3)-N'-(PEG4-NHS ester)-Cy5 is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups.
Target Antigen: PROTAC Linkers
Type: Reference compound
Related Pathways: PROTAC
Applications: Cancer-programmed cell death
Field of Research: Cancer
Assay Protocol: https://www.medchemexpress.com/n-azide-peg3-n-peg4-nhs-ester-cy5.html
Solubility: 10 mM in DMSO
Smiles: CC1(C2=C(N(/C1=C/C=C/C=C/C(C(C)(C3=C4C=CC=C3)C)=[N+]4CCOCCOCCOCCN=[N+]=[N-])CCOCCOCCOCCOCCC(ON5C(CCC5=O)=O)=O)C=CC=C2)C.[Cl-]
Molecular Weight: 937.52
References & Citations: [1]An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562
Shipping Conditions: Room temperature
Clinical Information: No Development Reported

Cat	Name
HY-141048	N-(Azide-PEG3)-N'-(PEG4-NHS ester)-Cy5
HY-141046	N-(m-PEG4)-N'-(PEG4-NHS ester)-Cy5
HY-141047	Bis-(N,N'-PEG4-NHS ester)-Cy5
HY-141063	N-(m-PEG4)-N'-(azide-PEG3)-Cy5
HY-141066	N-(azide-PEG3)-N'-(Mal-PEG4)-Cy5
HY-141041	N-(Azide-PEG3)-N'-(PEG4-acid)-Cy5
HY-141045	N-(m-PEG4)-N'-(PEG2-NHS ester)-Cy5
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