Platycodin D (Standard)

• Description:

  Platycodin D (Standard) is the analytical standard of Platycodin D. This product is intended for research and analytical applications. Platycodin D is a saponin isolated from Platycodon grandiflorus, acts as an activator of AMPKα, with anti-obesity property. WNT/β-catenin pathway mediates the anti-adipogenic effect of platycodin D[1][2].

• UNSPSC:

  12352005

• Target:

  AMPK; Reference Standards; Wnt

• Type:

  Reference compound

• Related Pathways:

  Epigenetics; Others; PI3K/Akt/mTOR; Stem Cell/Wnt

• Field of Research:

  Metabolic Disease

• Assay Protocol:

  https://www.medchemexpress.com/platycodin-d-standard.html

• Smiles:

  O=C ([C@]1 (CCC (C) (C) C2) [C@]2 ([H]) C3=CC[C@@]4 ([H]) [C@@] (C) (CC[C@]5 ([H]) [C@@]4 (C[C@H] (O) [C@H] (O[C@] ([C@@H] ([C@@H] (O) [C@@H]6O) O) ([H]) O[C@@H]6CO) C5 (CO) CO) C) [C@]3 (C) C[C@H]1O) O[C@H] (OC[C@H] (O) [C@@H]7O) [C@@H]7O[C@@] (O[C@@H] (C) [C@H] (O[C@@] (OC[C@@H] (O) [C@@H]8O[C@@] (OC[C@]9 (O) CO) ([H]) [C@@H]9O) ([H]) [C@@H]8O) [C@H]%10O) ([H]) [C@@H]%10O

• Molecular Formula:

  C57H92O28

• Molecular Weight:

  1225.32

• References & Citations:

  [1]Kim HL, et al. Platycodin D, a novel activator of AMP-activated protein kinase, attenuates obesity in db/db mice via regulation of adipogenesis and thermogenesis. Phytomedicine. 2019 Jan;52:254-263.|[2]Lee H, et al. WNT/β-catenin pathway mediates the anti-adipogenic effect of platycodin D, a natural compound found in Platycodon grandiflorum. Life Sci. 2011 Sep 12;89 (11-12) :388-94.|[3]Kim HL, et al. Platycodin D, a novel activator of AMP-activated protein kinase, attenuates obesity in db/db mice via regulation of adipogenesis and thermogenesis. Phytomedicine. 2019 Jan;52:254-263.|[4]Lee H, et al. WNT/β-catenin pathway mediates the anti-adipogenic effect of platycodin D, a natural compound found in Platycodon grandiflorum. Life Sci. 2011 Sep 12;89 (11-12) :388-94.

• Shipping Conditions:

  Room temperature

• Scientific Category:

  Reference Standards

• CAS Number:

  58479-68-8