Spiramine A

• Description :

  Spiramine A (Spiramine C acetate (ester) ) is a diterpene alkaloid with antitumor and antimicrobial activity. Spiramine A inhibits PAF-induced rabbit platelet aggregation in a concentration-dependent manner, with an IC50 vallue of 6.7 μM[1].

• CAS Number :

  [114531-28-1]

• Product Name Alternative :

  Spiramine C acetate (ester)

• UNSPSC :

  12352005

• Target :

  Bacterial

• Type :

  Natural Products

• Related Pathways :

  Anti-infection

• Applications :

  Cancer-programmed cell death

• Field of Research :

  Cancer

• Assay Protocol :

  https://www.medchemexpress.com/spiramine-a.html

• Solubility :

  10 mM in DMSO

• Smiles :

  C[C@@]12[C@]3([H])[C@@]([C@@](O4)([H])N5[C@@]1([H])OCC5)(CCC2)[C@@](CC6([H])C7=C)([H])[C@]([C@H]7OC(C)=O)(CC6)[C@@]4([H])C3

• Molecular Formula :

  C24H33NO4

• Molecular Weight :

  399.52

• References & Citations :

  [1]Li L, et al. Antiplatelet aggregation activity of diterpene alkaloids from Spiraea japonica. Eur J Pharmacol. 2002 Aug 2;449 (1-2) :23-8.

• Shipping Conditions :

  Room temperature

• Scientific Category :

  Natural Products

• Clinical Information :

  No Development Reported