mAChR-IN-1 (hydrochloride)

mAChR-IN-1 (hydrochloride)

• CAS Number: 119391-73-0
• UNSPSC Description: mAChR-IN-1 hydrochloride is a potent muscarinic cholinergic receptor (mAChR) antagonist, with an IC50 of 17 nM[1].
• Target Antigen: mAChR
• Type: Reference compound
• Related Pathways: GPCR/G Protein;Neuronal Signaling
• Field of Research: Neurological Disease
• Assay Protocol: https://www.medchemexpress.com/machr-in-1-hydrochloride.html
• Purity: 99.94
• Solubility: DMSO : 65 mg/mL (ultrasonic)|H2O : 1 mg/mL (ultrasonic;warming;heat to 60°C)
• Smiles: O=C(C(C1CCN(CC2=CC=C(I)C=C2)CC1)(C3=CC=CC=C3)CC4)NC4=O.[H]Cl
• Molecular Weight: 524.82
• References & Citations: [1]Wilson AA, et al. Synthesis and biological evaluation of [125I]- and [123I]-4-iododexetimide, a potent muscarinic cholinergic receptor antagonist. J Med Chem. 1989 May;32(5):1057-62.
• Shipping Conditions: Room Temperature
• Storage Conditions: 4°C (Powder, sealed storage, away from moisture and light)
• Clinical Information: No Development Reported