Phosphatidylinositol 4,5-bisphosphate | Gentaur

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Phosphatidylinositol 4,5-bisphosphate

CAT:

804-HY-114457-03

Size:

10 mg

Price:

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Phosphatidylinositol 4,5-bisphosphate

Alternative Name: 2-APV (lithium); DL-2-Amino-5-phosphonovaleric acid (lithium)
CAS Number: 245126-95-8
UNSPSC Description: Phosphatidylinositol 4,5-bisphosphate (L-alpha-Phosphatidylinositol-4,5-bisphosphate), a phospholipid component of cell membranes, is a substrate for phospholipase C (PLC) and phosphoinositide 3-kinase (PI3K) and as a primary messenger[1][2][3].
Target Antigen: PI3K
Type: Natural Products
Related Pathways: PI3K/Akt/mTOR
Field of Research: Others
Assay Protocol: https://www.medchemexpress.com/phosphatidylinositol-4-5-bisphosphate.html
Solubility: 10 mM in DMSO
Smiles: O=P(O)(O)O[C@H]1[C@@H]([C@H]([C@@H](O)[C@@H](OP(OC[C@@H](COC(CCCCCCCCCCCCCCCCC)=O)OC(CCC/C=C\C/C=C\C/C=C\C/C=C\CCCCC)=O)(O)=O)[C@@H]1O)O)OP(O)(O)=O
Molecular Weight: 1047.09
References & Citations: [1]Katan M, et, al. Phosphatidylinositol(4,5)bisphosphate: diverse functions at the plasma membrane. Essays Biochem. 2020 Sep 23;64(3):513-531. |[2]Arreola J, et, al. Wasted TMEM16A channels are rescued by phosphatidylinositol 4,5-bisphosphate Cell Calcium. 2019 Dec;84:102103. |[3]Kato M, et, al. Arabidopsis PCaP2 modulates the phosphatidylinositol 4,5-bisphosphate signal on the plasma membrane and attenuates root hair elongation. Plant J. 2019 Aug;99(4):610-625.
Shipping Conditions: Room temperature
Clinical Information: No Development Reported

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